Development and validation of a nomogram for predicting depressive symptoms in dentistry patients: A cross-sectional study.

Depressive symptoms are frequently occur among dentistry patients, many of whom struggle with dental anxiety and poor oral conditions. Identifying the factors that influence these symptoms can enable dentists to recognize and address mental health concerns more effectively. This study aimed to investigate the factors associated with depressive symptoms in dentistry patients and develop a clinical tool, a nomogram, to assist dentists in predicting these symptoms. Methods: After exclusion of ineligible participants, a total of 1355 patients from the dentistry department were included. The patients were randomly assigned to training and validation sets at a 2:1 ratio. The LASSO regression method was initially employed to select highly influrtial features. This was followed by the application of a multi-factor logistic regression to determine independent factors and construct a nomogram. And it was evaluated by 4 methods and 2 indicators. The nomograms were formulated based on questionnaire data collected from dentistry patients. Nomogram2 incorporated factors such as medical burden, personality traits (extraversion, conscientiousness, and emotional stability), life purpose, and life satisfaction. In the training set, Nomogram2 exhibited a Concordance index (C-index) of 0.805 and an Area Under the Receiver Operating Characteristic Curve (AUC) of 0.805 (95% CI: 0.775-0.835). In the validation set, Nomogram2 demonstrated an Area Under the Receiver Operating Characteristic Curve (AUC) of 0.810 (0.768-0.851) and a Concordance index (C-index) of 0.810. Similarly, Nomogram1 achieved an Area Under the Receiver Operating Characteristic Curve (AUC) of 0.816 (0.788-0.845) and a Concordance index (C-index) of 0.816 in the training set, and an Area Under the Receiver Operating Characteristic Curve (AUC) of 0.824 (95% CI: 0.784-0.864) and a Concordance index (C-index) of 0.824 in the validation set. Net Reclassification Improvement (NRI) and Integrated Discrimination Improvement (IDI) indicated that Nomogram1, which included oral-related factors (oral health and dental anxiety), outperformed Nomogram2. We developed a nomogram to predict depressive symptoms in dentistry patients. Importantly, this nomogram can serve as a valuable psychometric tool for dentists, facilitating the assessment of their patients' mental health and enabling more tailored treatment plans.

Corrigendum to "Influence of on emotions and behavior of adolescents with major depressive disorder" [Heliyon 9(5) (May 2023) e15890].

[This corrects the article DOI: 10.1016/j.heliyon.2023.e15890.].

Influence of on emotions and behavior of adolescents with major depressive disorder.

Background: Major depressive disorder in adolescents is characterized by high prevalence rate, high recurrence rate, high suicide rate and high disability rate. However, the recognition rate and cure rate are low, and the disease has a very bad influence on the family and society. The lack of psychiatrists and psychotherapists in villages and small towns makes it difficult to get timely and professional intervention and treatment for adolescent with major depressive disorder. Methods: A total of 84 adolescents with major depressive disorder who received treatment in the department of psychosomatic medicine of the Second Affiliated Hospital of Nanchang University participated in this survey, and they were divided into the control group and the intervention group by random number table. Adolescent Non-suicidal Self-injury Assessment Questionnaire (ANSSIAQ), Self-rating Questionnaire for Adolescent Problematic Mobile Phone Use (SQAPMPU), Screen for Child Anxiety Related Emotional Disorders (SCARED) and Depression Self-Rating Scale for Childhood (DSRS) were used to investigate the negative emotions and behavior of adolescents with major depressive disorder at baseline and intervention for 12 weeks. Results: There were no significant differences in the baseline information of adolescents (sex ratio, age, education level), including the total score of SCARED, DSRS and SQAPMPU, the total mean score of ANSSIAQ between the two groups (P > 0.05). After 12-week intervention, the score of SCARED, DSRS and SQAPMPU, the total mean score of ANSSIAQ in both groups were lower than that of the baseline, and the score of the intervention group showed a more obvious downward trend (P < 0.05). Conclusions: In-person and remote Satir family therapy not only effectively reduced the anxiety and depression level among participants, but also validly reduced their non-suicidal self-injury behavior and mobile phone use behavior. The results verified that the model we adopted can be well applied for the out-patient management of adolescents with major depressive disorder, especially in villages and small towns.

Nomogram reliability for predicting potential risk in postgraduate medical students with anxiety symptoms.

Purpose: This research aims to develop a Nomogram for exact anxiety symptoms prediction in postgraduate medical students so that they may be identified as high-risk individuals early and get focused care. Methods: Using a convenient sampling method, for case-control matching, 126 participants with anxiety symptoms and 774 participants of the same age and gender but without anxiety symptoms were designated as the case group and control group, respectively. Multivariable logistic regression analysis was utilized to identify influencing factors for anxiety symptoms, then used to design and verify a Nomogram of anxiety symptoms. Results: Multivariate logistic regression analysis showed that lack of social support (OR = 0.95, 95%CI: 0.91-0.99), low life satisfaction (OR = 0.91, 95%CI: 0.86-0.95), low subjective well-being (OR = 0.58, 95%CI: 0.41-0.83) and frequent tobacco and alcohol use (OR = 1.75, 95%CI: 1.10-2.80) were independent predictors of anxiety symptoms in postgraduate medical students (P < 0.05). The Nomogram risk prediction model based on the above four independent prediction factors was established, and the verified C-index (Concordance index) is 0.787 (95%CI: 0.744-0.803, P < 0.001). Conclusions: Anxiety symptoms in postgraduate medical students are influenced by various variables. The Nomogram prediction model has high accuracy, validity, and reliability, which can provide reference for predicting anxiety symptoms in postgraduate medical students.

Family function and life satisfaction of postgraduate medical students during the COVID-19 pandemic: the mediating role of meaning in life and depression.

Recent studies have documented life satisfaction of people have changed during the COVID-19 pandemic. However, it is unknown about the influential factors and mechanisms of life satisfaction of postgraduate medical students during the COVID-19 pandemic. There is a strong link among life satisfaction and individual quality of life and achievement, so it is important to explore the influence mechanism of life satisfaction of postgraduate medical students and explore ways to improve life satisfaction for the development of postgraduate medical students. The current study was based on the Circumplex Model of Marital and Family System, The Theory of Family Functioning, The Meaning Maintenance Model, The Theory of Personal Meaning and Existential Theory to construct theoretical framework and examine whether meaning in life and depression would mediate the link between family function and postgraduate medical students' life satisfaction. By convenient sampling method, a total of 900 postgraduate medical students (Mage = 27.01 years, SD = 3.33) completed questionnaires including Family APGAR Scale, Chinese Version of Meaning In Life Questionnaire, Patient Health Questionnaire, and Satisfaction With Life Scale. In this study, SPSS 25.0 was used for correlation analysis, regression analysis and common method bias test, and AMOS 23.0 was used for structural equation modeling analysis. The results showed that (a) family function could predict life satisfaction of postgraduate medical students significantly; (b) both meaning in life and depression mediated the association between family function and life satisfaction in a parallel manner; (c) meaning in life and depression sequentially mediated the link between family function and life satisfaction of postgraduate medical students. The study illuminates the role of meaning in life and depression in improving life satisfaction and implies that it is necessary to focus on the changes of life satisfaction of postgraduate medical students during the COVID-19 pandemic, and medical educator can improve the sense of meaning in life of postgraduate medical students through improving their family function, further decreasing the risk of depression, finally improving their life satisfaction.

The structural characteristics and influential factors of psychological stress of urban residents in Jiangxi province during the COVID-19 pandemic: cross sectional study.

AIMS: To explore the structural characteristics and influential factors of psychological stress of urban residents in Jiangxi province during the COVID-19 pandemic through a survey of psychological stress, personality traits, family function and life satisfaction. METHODS: By the convenient sampling, 1422 urban residents from Jiangxi province were assessed with Eysenck Personality Questionnaire Short Scale (EPQ-RSC), Psychological Questionnaires for Emergent Events of Public Health (PQEEPH), Family APGAR Scale (APGAR) and Satisfaction With Life Scale (SWLS). The relation among personality traits, psychological stress, family function and life satisfaction during the COVID-19 pandemic was analyzed by using the canonical correlation analysis and the serial mediation model. RESULTS: (1) Among the estimated correlation coefficients, the first two pairs were significant (P < 0.001 in each). (2) In the first pair of canonical variables, the loadings of neuroticism and neurasthenia were the higher (0.94, 0.70). (3) Neuroticism and life satisfaction mediated the relationship between family function and neurasthenia (ß neuroticism = -0.174; 95%CI:-0.224, -0.134; ß life satisfaction = -0.034, 95%CI:-0.012, -0.062), respectively. In addition, serial mediation analyses indicated that the association of family function and neurasthenia is mediated by neuroticism and life satisfaction in a sequential manner (ß = -0.010; 95%CI:-0.020, -0.004). CONCLUSIONS: During the COVID-19 pandemic, neuroticism was closely related to psychological stress of urban residents, especially neurasthenia. In addition, the serial mediating effect of neuroticism and life satisfaction played an important role in the process of family function influencing neurasthenia. These findings contributed to a more comprehensive understanding of the influential factors for psychological stress of urban residents during the COVID-19 pandemic.

Social support and subjective well-being among postgraduate medical students: the mediating role of anxiety and the moderating role of alcohol and tobacco use.

Medical students often face pressures from various sources in the course of postgraduate studies, and these factors have a negative impact on their subjective well-being. Previous researches have revealed that social support is a vital factor influencing subjective well-being, but unfortunately the underlying mechanism for this is unclear, especially for postgraduate medical students. The current study has inspected the effects of social support on subjective well-being of postgraduate medical students, the mediating role of anxiety and the moderating role of alcohol and tobacco use in the association between social support and subjective well-being of postgraduate medical students. A sample of 900 postgraduate medical students (Mage = 27.01 years, SD = 3.33) from The Second Affiliated Hospital of Nanchang University completed the Social Support Rating Scale, the Generalized Anxiety Disorder-7, the Tobacco and Alcohol Use Questionnaire and the Subjective Well-Being Scale. Analysis of the structural equation model revealed that anxiety partially mediated the relationship between social support and subjective well-being of postgraduate medical students, while alcohol and tobacco use moderated the relationship between anxiety and subjective well-being of postgraduate medical students. This study revealed how social support act upon subjective well-being of postgraduate medical students. This study provides a theoretical basis for promoting and enhancing the subjective well-being of postgraduate medical students.

Microstructure Evolution of Ti-45Al-8.5Nb-0.2W-0.2B-0.02Y Alloy during Long-Term Thermal Exposure.

The hot-rolled alloy Ti-45Al-8.5Nb-0.2W-0.2B-0.02Y was exposed to 700 °C air for up to 10,000 h. The changes in microstructure were observed using scanning and transmission electron microscopies. It was found that the α2 laths, α2 + γ lamellae, and B2(ω) structure of the alloy showed thermodynamic instability. There were three types of phase transformation in the alloy during long-term thermal exposure. The first was α2 → γ, which occurs in the interior and boundary of the α2 + γ lamellae. The second was α2 + γ → B2(ω), which occurs on the α2 + γ boundary. In addition, B2(ω) also precipitates on the γ/γ interfaces. The third was B2(ω) → γ, which describes the precipitation of micron-scale γ phases in the B2(ω) area after thermal exposure of 5000 h. The volume fraction and size of the B2(ω) area and equiaxed γ grains continued to increase throughout the exposure process. Large-sized γ grains and a B2 area of tens of microns appeared in the microstructure after long-term thermal exposure. The volume fractions of the B2 area and the equiaxed γ grains after thermal exposure of 10,000 h reached 16.8% and 63.2%, respectively.